TOKYO, May 16 (Xinhua) -- Tokyo stocks closed lower Wednesday following a sell-off on Wall Street overnight as the long-term U.S. government bond yield spiked to its highest level since 2011 and on concerns after a suspension of inter-Korean ministerial talks.

The 225-issue Nikkei Stock Average lost 100.79 points, or 0.44 percent, from Tuesday to close the day at 22,717.23.

The broader Topix index of all First Section issues on the Tokyo Stock Exchange, meanwhile, dropped 4.80 points, or 0.27 percent, lower to finish at 1,800.35.

Mining, warehousing and harbor transportation service, and information and communication-linked issues comprised those that declined the most by the close of play.